Table 5.

Change in each outcome associated with each IQR increase or decrease in ambient temperature, by moving average of time before outcome measurement was made, by season.

	Biomarkers and moving averages evaluated	Winter (December–February)				Summer (June–August)
		N Subjects (N Subject-Visits)	IQR (°C)	Change in Biomarker per IQR increase	95% CI	N Subjects (N Subject-Visits)	IQR (°C)	Change in Biomarker per IQR increase	95% CI
WHOLE SESSION	HRT(ms/RR)a
	0–5	30 (118)	7.9	−0.47	−1.71, 0.77	41 (121)	7.2	−0.10	−1.83, 1.63
	0–23		7.3	−0.86	−2.08, 0.35		4.3	−0.32	−1.29, 0.65
	0–47		6.9	−0.53	−1.74, 0.69		4.2	−0.66	−1.74, 0.42
	0–71		6.5	−0.82	−2.06, 0.41		3.8	−0.61	−1.71, 0.50
	0–95		6.1	−1.21*	−2.41, −0.01		3.5	−0.60	−1.75, 0.55
	0–167 (1 week)		5.5	−1.02	−2.27, 0.24		3.1	−0.86	−2.30, 0.58
	0–503 (3 weeks)		4.6	−0.34	−1.94, 1.25		2.5	−0.07	−1.76, 1.62
	DC(ms)
	0–5	30 (276)	7.9	−0.14	−0.32, 0.04	41 (379)	7.2	−0.10	−0.29, 0.09
	0–23		7.3	−0.11	−0.30, 0.07		4.3	−0.06	−0.18, 0.05
	0–47		6.9	−0.12	−0.30, 0.07		4.2	−0.09	−0.21, 0.04
	0–71		6.5	−0.12	−0.32, 0.08		3.8	−0.08	−0.20, 0.05
	0–95		6.1	−0.12	−0.33, 0.09		3.5	−0.06	−0.19, 0.06
	0–167 (1 week)		5.5	−0.09	−0.31, 0.12		3.1	−0.05	−0.20, 0.09
	0–503 (3 weeks)		4.6	−0.09	−0.34, 0.16		2.5	−0.01	−0.20, 0.18
	rMSSD (ms)
	0–5	30 (283)	7.9	−0.17	−4.95, 4.62	41 (390)	7.2	−9.66**	−15.60, −3.72
	0–23		7.3	−1.43	−6.28, 3.42		4.3	−6.56**	−10.09, −3.03
	0–47		6.9	−0.57	−5.49, 4.35		4.2	−6.77**	−10.63, −2.91
	0–71		6.5	1.07	−4.17, 6.30		3.8	−6.32**	−10.19, −2.44
	0–95		6.1	2.32	−3.14, 7.77		3.5	−6.45**	−10.33, −2.56
	0–167 (1 week)		5.5	4.37	−1.28, 10.01		3.1	−7.01**	−11.52, −2.49
	0–503 (3 weeks)		4.6	6.80*	0.22, 13.39		2.5	−4.36	−10.26, 1.53

^aNote: Since HRT is measured only when premature ventricular contractions (PVC) occur, these analyses include only those subject-visits with 1 or more PVCs.

^†p<0.10

^*p<0.05

^**p<0.01