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Kaplan-Meier analysis showed a significant association between intensity of reactive stroma and the occurrence of castration-resistant prostate cancer in tumors with Gleason score of 6–7 (log-rank P = 0.009, (a). Patients with higher vimentin expression (log-rank P = 0.044, (b) or lower desmin expression (log-rank P = 0.045, (c) had a shorter disease-free period.
