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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Nat Chem. 2014 Jun 1;6(7):635–643. doi: 10.1038/nchem.1963

Figure 6. Adjuvant-active quillaic acid derivative 16 localizes to the injection site and lymph nodes in mice while adjuvant-attenuated oleanolic acid derivative 18 does not.

Figure 6

In vivo biodistribution in mice of active adjuvant [131I]-16 ([131I]-SQS-1-0-5-18) and attenuated adjuvant [131I]-18 ([131I]-SQS-1-7-5-18) at 24 h post-injection in the presence of 20 μg of OVA; error bars indicate standard deviation from mean for five mice; statistical significance indicated graphically only for lymph nodes and injection site for clarity: * = p ≤ 0.05: lymph nodes, injection site, skin; ** = p < 0.01: lungs, spleen, stomach, muscle, bone; *** = p < 0.001: blood, heart.