A: Representative photograph taken at necropsy 1 year after pneumonectomy demonstrates substantial growth of the right accessory lobe. RLL = right lower lobe; RAL = right accessory lobe. The circle outlines the RAL.
B: Representative isosurface renderings of the CT scans at 2 months and at 1 year following left pneumonectomy demonstrates growth and expansion of right lower lobe into left chest cavity (white arrows). Yellow arrows indicate the residual left main stem bronchus. Scans represent typical results obtained in 6 mice evaluated at 2 months and 7 mice evaluated 1 year after pneumonectomy.
C: Representative reconstructive regions of interest on the CT scans highlighting the right accessory lobe (yellow) one year after pneumonectomy and in an age-matched naïve control mouse.