Figure 1.

Left panel: OCT image of a retina in a control, LHON, and CRD subject. In each panel, the inset image in the lower left shows the position of the scan line. The main image shows the cross-section. The blue lines outline the RNFL. The red line shows the borderline between inner segment/outer segment (IS/OS) photoreceptors. (A) Control. (B) LHON. The retinal nerve fiber layer is very thin whereas the IS/OS lines are similar to the control. (C) CRD. The IS/OS line is missing, but the RNFL thickness is similar to controls. Right panel: Visual fields measured by Goldmann perimetry. Black depicts visual field regions with no sensitivity to the target.