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. 2014 Oct 16;3:245. [Version 1] doi: 10.12688/f1000research.5544.1

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Copyright: © 2014 Chevalier M et al.

This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Data associated with the article are available under the terms of the Creative Commons Zero "No rights reserved" data waiver (CC0 1.0 Public domain dedication).

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Figure 3. — A. Time course of a typical experiment in Nav1.5-expressing cells showing the effects of ranolazine 30 μM, TTX 30 μM, and veratridine 1 μM on I _{Na late}. B. Averaged Fourier transforms of multiple traces recorded in different conditions in the experiment shown in A: 1. initial control; 2. ranolazine 30 μM; 3. TTX 30 μM; 4. veratridine 1 μM; 5. veratridine 50 μM. C. Fluctuation analysis of individual traces recorded during the five distinct periods shown in A allowed the distinction of individual channel gating events and the computation of the average open probability p and the average number of channels n for each condition.