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. 2014 Jul 18;592(Pt 19):4201–4220. doi: 10.1113/jphysiol.2014.276220

Figure 5. Role for cAMP in modifying adult ipRGC light responses.

Figure 5

A and B, example spike rasters (A) and mean spike count data (B) for light-stimulated ipRGCs (N = 3; n = 14) recorded from adult (>2 months old) rat retinas before, during and after 5 min treatment with 10 μm forskolin. C and D, similarly, example rasters (C) and mean spike count data (D) for adult ipRGCs (N = 3; n = 9) treated with 1 mm 8-Br-cAMP for 5 min. **P < 0.01, *P < 0.05, one-way repeated-measures ANOVA, Holm–Sidak. All light responses (control, drug treatment, washout) in these data were recorded in the presence of synaptic blocker cocktail to confirm recordings were from ipRGCs. Stimulus was blue light (470 nm; 3.9 × 1015 photons s−1 cm−2).