Table 5.
Age of AD onset (AoO) by cancer history.
| Method | Kaplan-Meier | Cox regression | ||||
|---|---|---|---|---|---|---|
| Measure | Median AoO | 95% CI | χ2 | P | AD OR | |
| All: CA− | 81.7 | 80.7–82.8 | 20.9 | 0.000 | 1.5 | 1.3–1.8 |
| All: CA+ | 84.7 | 83.4–86.0 | *Ref | |||
| All: 0 CA− | 81.7 | 80.7–82.8 | 22.2 | 0.000 | 2.0 | 1.3–3.0 |
| All: 1 CA+ | 84.3 | 83.2–85.4 | 1.3 | 0.9–2.1 | ||
| All: 2 CA+ | 85.7 | 82.4–88.9 | Ref | |||
| NMSC: CA− | 82.4 | 81.5–83.3 | 13.3 | 0.000 | 1.6 | 1.2–2.1 |
| NMSC: CA+ | 85.7 | 82.7–88.6 | *Ref | |||
| Prostate: CA− | 82.8 | 82.0–83.7 | 4.4 | 0.037 | 1.4 | 1.0–1.8 |
| Prostate: CA+ | 84.7 | 82.6–86.9 | Ref | |||
Values for Median AoO and 95% CI are given in years. AoO, age of onset; CI, confidence interval; AD OR, odds ratio of developing Alzheimer's disease;
*
Ref, reference variable for odds ratio calculation.