Table 1.
Control | 2nd week | 4th week | 6th week | 8th week | 10th week | 12th week | |
---|---|---|---|---|---|---|---|
Ballooning of purkinje cell | − | ++ | ++ | ++ | ++ | ++ | ++ |
Chromatolysis | − | ++ | ++ | +++ | ++++ | ++++ | ++++ |
Vacuolation | − | − | ++ | ++ | +++ | +++ | ++++ |
Necrosis/Apoptosis | − | ++ | ++ | +++ | +++ | ++++ | ++++ |
Pyknosis/Dark purkinje cell | − | ++ | ++ | +++ | +++ | ++++ | ++++ |
Gliosis | − | + | ++ | ++ | +++ | ++++ | ++++ |
Neuronophagia | − | − | ++ | ++ | +++ | ++++ | ++++ |
−, Nil (less than 5%); +, minimal (5–10%); ++, mild (10–20%); +++, moderate (20–30%); ++++, severe (more than 30%).