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. Author manuscript; available in PMC: 2014 Oct 31.
Published in final edited form as: Am J Physiol Gastrointest Liver Physiol. 2007 Aug 16;293(4):G894–G902. doi: 10.1152/ajpgi.00133.2007

Fig. 3.

Fig. 3

Changes of hepatic methionine metabolism. Male C57BL/6 mice were fed with high-sucrose diet in the presence or absence of betaine supplementation (1%) in the drinking water for 16 wk. Liver samples were homogenized with 4% metaphosphoric acid and hepatic S-adenosylmethionine (SAM) and homocysteine contents were assayed by high-performance liquid chromatography. A: changes of hepatic SAM levels. Data are means ± SD (n = 8). Bars with different letters differ significantly (P < 0.05). B: hepatic homocysteine levels. Data are means ± SD (n = 8). Bars with different letters differ significantly (P < 0.05).