Table 3. In vitro activity of 4 antifungal drugs against biofilm forming cells of 54 clinical isolates of Trichosporon spp.
Species (Number of isolates) | MIC (μg/ml) | |||||||||||
Fluconazole | Itraconazole | Voriconazole | Amphotericin B | |||||||||
Interval | MIC50 | MIC90 | Interval | MIC50 | MIC90 | Interval | MIC50 | MIC90 | Interval | MIC50 | MIC90 | |
T. asahii (36) | - | >1024 | >1024 | - | >16 | >16 | - | >64 | >64 | - | >32 | >32 |
T. faecale (6) | - | >1024 | >1024 | - | >16 | >16 | - | >64 | >64 | - | >32 | >32 |
T. asteroides (5) | - | >1024 | >1024 | - | >16 | >16 | - | >64 | >64 | - | >32 | >32 |
T. inkin (4) | - | >1024 | >1024 | - | >16 | >16 | - | >64 | >64 | - | >32 | >32 |
T. dermatis (2) | - | >1024 | >1024 | - | >16 | >16 | - | >64 | >64 | - | >32 | >32 |
T. coremiiforme (1) | - | >1024 | >1024 | - | >16 | >16 | - | >64 | >64 | - | >32 | >32 |
MIC50: Minimal inhibitory concentration capable of inhibiting growth of 50% of isolates.
MIC90: Minimal inhibitory concentration capable of inhibiting growth of 90% of isolates.