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. 2014 Oct 31;9(10):e108983. doi: 10.1371/journal.pone.0108983

Table 2. Comparisons between female and male with and without IHD.

Non-IHD IHD
Female (n = 144) Male (n = 283) P-Value Female (n = 246) Male (n = 1,415) P-Value
Age (yrs ± SD) 67.5±13.5 60.9±12.3 P<0.001 70.4±10.2 64.4±10.3 P<0.001
Body mass index (kg/m2 ± SD) 21.9±3.2 23.7±3.6 P<0.001 23.0±3.5 24.5±3.4 P<0.001
Current smoker (%) 8.3 28.6 P<0.001 12.6 25.1 P<0.001
Current+past smoker (%) 19.4 70.7 P<0.001 28.5 77.0 P<0.001
Hypertension (%) 66.0 64.0 NS 77.6 76.3 NS
Diabetes Mellitus (%) 27.1 29.7 NS 42.7 45.5 NS
Dyslipidemia (%) 43.1 47.0 NS 74.0 76.3 NS
s-Cr (mg/dl ± SD) 1.6±2.5 1.6±2.3 P<0.001 1.5±2.3 1.6±2.3 P<0.001
HbA1c (% ± SD) 5.7±1.1 5.8±1.1 NS 5.9±0.8 6.1±1.1 P<0.05
BNP (pg/ml ± SD) 319.5±650.4 305.5±650.9 P<0.05 303.2±668.2 132.3±327.4 P<0.001
HD & CAPD (%) 13.2 9.5 NS 13.0 8.7 P<0.05
LVEF (% ± SD) 59.3±12.3 54.4±15.1 P<0.001 59.5±11.6 57.4±10.7 P<0.01
Heart rate (beat/min ± SD) (At LVG) 73.3±14.0 74.4±17.6 NS 72.5±14.3 70.3±13.4 P<0.05
LVEDP (mmHg ± SD) (At Pre LVG) 16.4±7.0 16.6±7.3 NS 16.1±6.9 15.5±6.1 NS
LVESVI (ml/m2 ± SD) 31.7±19.8 39.0±27.2 P<0.01 27.3±17.0 29.1±16.2 NS
Prior myocardial infarction (%) 0 0 35.8 38.9 NS
Prior PCI (%) 0 0 35.8 46.1 P<0.01
Prior CABG 0 0 15.9 12.0 NS
Coronary spastic angina 0 0 12.6 7.8 P<0.05
Prior valve repair (%) 7.6 3.5 NS 1.6 0.5 P<0.05
Valvular heart disease (%) 38.2 26.1 P = 0.01 6.9 2.8 P = 0.001
Congenital heart disease (%) 8.3 3.5 P<0.05 0.4 0.4 NS
Cardiomyopathy (%) 20.8 23.7 NS 3.3 1.8 NS
AF (%) 19.4 21.2 NS 4.9 5.7 NS
Calcium-channel blockers (%) 43.1 37.1 NS 59.8 60.8 NS
ACE-inhibitors (%) 14.6 15.2 NS 18.3 21.8 NS
Angiotensin Receptor Blockers (%) 44.4 34.6 P<0.05 42.7 40.7 NS
Nitrates (%) 8.3 9.5 NS 28.5 26.2 NS
Nicorandil (%) 4.2 4.2 NS 23.2 19.9 NS
Beta-blockers (%) 20.8 17.7 NS 28.9 35.3 P<0.05
Statins (%) 29.9 19.4 P<0.05 57.7 59.6 NS
Fibrates (%) 1.4 4.2 NS 1.2 3.8 P<0.05
Diuretics (%) 38.2 29.0 NS 28.5 17.5 P<0.001
Oral Hypoglycemic Agents (%) 9.7 12.4 NS 18.3 24.5 P<0.05
insulin (%) 6.9 4.2 NS 10.6 9.8 NS
Number of vessels disease (0–3) 0 0 0.96±0.96 0.95±097 NS

s-Cr, Serum creatinine; BNP, B-type natriuretic peptide; HD & CAPD, Hemodialysis & continuous ambulatory peritoneal dialysis; LVEF, Left ventricular ejection fraction; LVEDP, Left ventricular end-diastolic pressure; LVESVI, Left ventricular end-systolic volume Index; PCI, Percutaneous coronary intervention; CABG, Coronary artery bypass graft;AF, Atrial Fibrillation.