Table 1. Aldehyde Tag Is Well-Tolerated when Inserted into a Variety of Locations along the Antibody Backbone.

tag designation	tag domain	residues bordering taga	% aggregation
A	CH1	G118, V121	0
B	CH1	P123, S128	0
C	CH1	A165, G169	2.3
D	CH2	D283, E285	31.5
E	CH2	N344, A349	4.5
F	CH3	G361, E366	76
G	C-terminus	K478	7
LC	LC	A153, Q155	0

^aKabat numbering.