Table 2. Number of women recruited per group.
Group | Number of women | % of total recruited | % of group |
Vascular Disruption Cases | |||
Gastroschisis | 59 | 11.4 | 27.7 |
Facial cleft | 44 | 8.5 | 20.7 |
Renal anomaly | 41 | 7.9 | 19.2 |
Cardiac defect | 39 | 7.5 | 18.3 |
Non NTD Central Nervous System anomaly | 20 | 3.9 | 9.4 |
*Other vascular | 10 | 1.9 | 4.7 |
Total Vascular Disruption Cases | 213 | 41.2 | 100 |
Non-Vascular Disruption Control Group | |||
Exomphalos | 30 | 5.8 | 21.0 |
Congenital Diaphragmatic Hernia | 29 | 5.6 | 20.3 |
NTD | 25 | 4.8 | 17.5 |
Talipes | 23 | 4.4 | 16.0 |
**Aneuploidy | 21 | 4.1 | 14.7 |
ΔGenetic | 15 | 2.9 | 10.5 |
Total Non Vascular Disruption Controls | 143 | 27.7 | 100 |
Normal Controls | |||
Normal structure and karyotype | 161 | 31.1 | - |
Total Control Group (Non-Vascular Disruption and Normal) | 304 | 58.8 | - |
Total recruited | 517 | 100 | - |
NTD: neural tube defect.
* Transverse limb defects (7 cases), bowel atresia (3 cases: duodenal atresia or ileal atresia) .
** Trisomy 21 (10 cases), trisomy 18 (2 cases), 1 case each of trisomy 13, 45 X0, XXX, triploidy, unbalanced translocation, 15q deletion, terminal deletion of chromosome 5.
Δ Skeletal dysplasia (8 cases), multiple abnormalities (6 cases), autosomal dominant polycystic kidney disease (2 cases).
Cardiac anomalies included large septal defects, hypoplastic left or right heart, Ebstein's anomaly, tetralogy of Fallot, transposition of the great arteries, left atrial isomerism, valvular atresias and double outlet right ventricle.
Other CNS anomalies included agenesis of corpus callosum, Dandy Walker spectrum, cerebellar hypoplasia, posterior fossa cyst, porencephalic cyst, severe ventriculomegaly and holoprosencephaly.
Renal anomaly: multicystic or dysplastic kidneys, lower urinary outflow tract obstruction.