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. 2014 Oct 31;9(10):e111038. doi: 10.1371/journal.pone.0111038

Table 2. Number of women recruited per group.

Group Number of women % of total recruited % of group
Vascular Disruption Cases
Gastroschisis 59 11.4 27.7
Facial cleft 44 8.5 20.7
Renal anomaly 41 7.9 19.2
Cardiac defect 39 7.5 18.3
Non NTD Central Nervous System anomaly 20 3.9 9.4
*Other vascular 10 1.9 4.7
Total Vascular Disruption Cases 213 41.2 100
Non-Vascular Disruption Control Group
Exomphalos 30 5.8 21.0
Congenital Diaphragmatic Hernia 29 5.6 20.3
NTD 25 4.8 17.5
Talipes 23 4.4 16.0
**Aneuploidy 21 4.1 14.7
ΔGenetic 15 2.9 10.5
Total Non Vascular Disruption Controls 143 27.7 100
Normal Controls
Normal structure and karyotype 161 31.1 -
Total Control Group (Non-Vascular Disruption and Normal) 304 58.8 -
Total recruited 517 100 -

NTD: neural tube defect.

* Transverse limb defects (7 cases), bowel atresia (3 cases: duodenal atresia or ileal atresia) .

** Trisomy 21 (10 cases), trisomy 18 (2 cases), 1 case each of trisomy 13, 45 X0, XXX, triploidy, unbalanced translocation, 15q deletion, terminal deletion of chromosome 5.

Δ Skeletal dysplasia (8 cases), multiple abnormalities (6 cases), autosomal dominant polycystic kidney disease (2 cases).

Cardiac anomalies included large septal defects, hypoplastic left or right heart, Ebstein's anomaly, tetralogy of Fallot, transposition of the great arteries, left atrial isomerism, valvular atresias and double outlet right ventricle.

Other CNS anomalies included agenesis of corpus callosum, Dandy Walker spectrum, cerebellar hypoplasia, posterior fossa cyst, porencephalic cyst, severe ventriculomegaly and holoprosencephaly.

Renal anomaly: multicystic or dysplastic kidneys, lower urinary outflow tract obstruction.