Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Superposition of ss-IDI-2 in complex with IPP and FMNH2 (purple) and sp-IDI-2 in complex with reduced cofactor (green) and sulfate ions (stick and balls). These ions are stabilized by ionic salt bridges with guanine from R5, and by interactions with amide moiety of Q149 and imidazole ring of H9. Interestingly, they lie at the same positions as the C2-atom and the β-phosphate within IPP observed in ss-IDI-2•IPP structure inside the binding pocket (sp numbering/ss numbering).
