Table 1.
Clinical characteristics of PPA and PPAOS
naPPA | svPPA | lvPPA | PPAOS | ||
---|---|---|---|---|---|
Clinical features | Agrammatism | + | − | − | − |
Apraxia of speech | + | − | − | + | |
Impaired comprehension | + (syntactically complex sentences) | + (single words) | +/− | − | |
Impaired naming | − | + | +/− | − | |
Impaired object knowledge | − | + | − | − | |
Paraphasia | + | +/− | + | − | |
Speech rate | Significantly reduced | Normal | Moderately reduced | Significantly reduced | |
Impaired repetition | + (single words) | − | + (sentences and phrases) | + (single words) | |
Other | Surface dyslexia or dysgraphia |
Abbreviations: naPPA=non-fluent/agrammatic variant of primary progressive aphasia; svPPA = semantic variant of primary progressive aphasia; lvPPA = logopenic variant of primary progressive aphasia; PPAOS = primary progressive apraxia of speech