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Mdm2 (B, E, H, K) and p53 (C, F, I, L) expression in sarcomas. (A–C) Mdm2-positive, p53-negative de novo osteosarcoma. (D–F) Mdm2-positive, p53-positive de novo myxofibrosarcoma. (G–I) Mdm2-negative, p53-positive radiation-induced osteosarcoma. (J–L) Mdm2-negative, p53-negative radiation-induced fibrosarcoma.
