Table 1.

Radiation-induced sarcomas of head and neck

Tumor type	Site	Age (yr)/Sex	Previous tumor	Treatment	Interval between RT & sarcoma
Osteosarcoma	Mandible	61/F	Malignant lymphoma of palatine tonsil	CT and RT	9 yr 3 mo
Osteosarcoma	Mandible	17/M	Pleomorphic liposarcoma of parotid gland	Wide excision and RT	4 yr
Osteosarcoma	Skull	33/F	Astrocytoma	Tumor resection and RT	3 yr 6 mo
UPS	Nasal cavity	22/M	Olfactory neuroblastoma	Medial maxillectomy, CT and RT	3 yr 3 mo
UPS	Nasopharynx	42/F	Nasopharyngeal carcinoma	RT	6 yr
UPS	Posterior neck	60/M	Nasopharyngeal carcinoma	RT	5 yr 5 mo
Fibrosarcoma	Hard palate	50/F	Malignant melanoma of maxillary sinus	Partial maxillectomy, CT and RT	17 yr
MFS	Submandibular area	51/F	Nasopharyngeal carcinoma	RT	12 yr

F, female; CT, chemotherapy; RT, radiotherapy; M, male; UPS, undifferentiated pleomorphic sarcoma; MFS, myxofibrosarcoma.