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. 2014 Oct 31;9(10):e111459. doi: 10.1371/journal.pone.0111459

Table 2. Indices of systemic inflammationa.

Pre-op 2 h post-op 24 h post-op Post-op day 1
CRP
median (IQR) mg/L 2 (1–4) 54 (39.5–70)
WCC mean
mean (SD), 103/µl 7.3±1.8 8.2±2.3*
IL-6
median (IQR), pg/ml 19.7 (6.9–35.0) 101.5 (52.9–244)*** 61.1 (33.3–173.2)***
IL-8
median (IQR) pg/ml 4.4 (2.2–6.5) 55.5 (30.3–21)*** 12.7 (6.4–23.2)** , #
IL-10
median (IQR) pg/ml 4.8 (2.3–15.7) 63.7 (40.5–110)*** 32.2 (21.6–47.4)*** , #
a

n = 32 patients undergoing cardiac surgery requiring cardiopulmonary bypass.

CRP, c-reactive protein; WCC, white cell count; IL-6, -8,-10, interleukin-6, -8,-10; IQR = interquartile range, SD = standard deviation.

*p = 0.0378, **p<0.01, ***p<0.001, p<0.0001, compared with pre-op levels.

#

p<0.05, compared with 2 h.