Table 2. Indices of systemic inflammationa.
Pre-op | 2 h post-op | 24 h post-op | Post-op day 1 | |
CRP | ||||
median (IQR) mg/L | 2 (1–4) | 54 (39.5–70)† | ||
WCC mean | ||||
mean (SD), 103/µl | 7.3±1.8 | 8.2±2.3* | ||
IL-6 | ||||
median (IQR), pg/ml | 19.7 (6.9–35.0) | 101.5 (52.9–244)*** | 61.1 (33.3–173.2)*** | |
IL-8 | ||||
median (IQR) pg/ml | 4.4 (2.2–6.5) | 55.5 (30.3–21)*** | 12.7 (6.4–23.2)** , # | |
IL-10 | ||||
median (IQR) pg/ml | 4.8 (2.3–15.7) | 63.7 (40.5–110)*** | 32.2 (21.6–47.4)*** , # |
n = 32 patients undergoing cardiac surgery requiring cardiopulmonary bypass.
CRP, c-reactive protein; WCC, white cell count; IL-6, -8,-10, interleukin-6, -8,-10; IQR = interquartile range, SD = standard deviation.
*p = 0.0378, **p<0.01, ***p<0.001, †p<0.0001, compared with pre-op levels.
p<0.05, compared with 2 h.