Table I.

Cigarettes per day and urinary nicotine and nicotine metabolite concentrations by racial/ethnic group^a

	AAs (n = 364)	NHs (n = 311)	Whites (n = 437)	Latinos (n = 453)	JAs (n = 674)
	Median (25th–75th%)	Median (25th–75th%)	Median (25th–75th%)	Median (25th–75th%)	Median (25th–75th%)
Total nicotine	5.44 (2.9–11.0)	6.19 (3.32–11.4)*	5.42 (3.04–8.80)	4.41 (1.92–7.72)*	6.38 (3.54–11.8)*
Nicotine glucuronide/ total nicotine	0.26 (0.12–0.42)b,*	0.30 (0.18–0.42)*	0.34 (0.21–0.48)	0.37 (0.25–0.54)c*	0.32 (0.21–0.44)d
Total cotinine	10.7 (6.19–15.4)	9.85 (5.62–14.1)	10.7 (5.54–17.2)	9.34 (4.49–14.8)*	7.78 (4.34–12.8)*
Cotinine glucuronide/ total cotinine	0.48 (0.28–0.61)b,*	0.55 (0.45–0.64)*	0.58 (0.48–0.69)	0.60 (0.49–0.69)e	0.51 (0.41–0.60)*
Total 3-HCOT	22.7 (11.5–44.4)*	10.6 (5.61–19.9)*	16.9 (8.77–30.1)	16.4 (7.71–27.8)	6.98 (2.37–15.6)*
3-HCOT glucuronide/ total 3HCOT	0.27 (0.21–0.35)b	0.19 (0.14–0.25)*	0.24 (0.18–0.30)	0.23 (0.17–0.29)	0.18 (0.12–0.24)f*
Nicotine N-oxide	2.65 (1.37–4.89)*	1.88 (0.96–3.56)	1.76 (0.90–3.04)	1.49 (0.64–3.07)*	2.16 (1.14–3.6)*
TNEs	44.4 (27.1–74.0)*	30.3 (19.4–46.8)*	36.3 (21.90–61.5)	32.2 (20.8–53.6)	27.3 (15.8–43.4)*
Products of C-oxidation	0.81 (0.72–0.87)	0.73 (0.64–0.81)*	0.79 (0.71–0.86)	0.81 (0.72–0.88)	0.66 (0.47–0.79)*
CPD	10.0 (5–15)*	15.0 (9–20)*	20.0 (10–20)	7.07 (4.0–12)*	12.0 (9–20)*

^aMetabolite values are expressed in nmol/ml, 3-HCOT, trans 3′-hydroxycotinine, TNE is the sum of total nicotine, total cotinine, total 3-HCOT and nicotine N-oxide, products of C-oxidation are the sum of total cotinine and total 3-HCOT divided by TNE.

^b n = 363.

^c n = 450.

^d n = 673

^e n = 452.

^f n = 666.

*P-value for comparison with Whites (P < 0.05).