Table 1. Cytokine expression following OxC-beta treatment and LPS challenge.
| Conc.2 | TNFα | IL-6 | IL-1β | IFNγ | ||||
| µM | pg/mL3 | Fold4 | pg/mL3 | Fold4 | pg/mL3 | Fold4 | pg/mL3 | Fold4 |
| 0.0 | 1471±171 | 1.00 | 37.7±1.9 | 1.00 | 1194±46 | 1.00 | 20.9±0.6 | 1.00 |
| 0.1 | 1840±3# | 1.25 | 49.4±3.9* | 1.31 | 1425±117 | 1.19 | 21.0±0.1 | 1.00 |
| 0.5 | 1846±7# | 1.25 | 56.1±2.8* | 1.48 | 1669±78* | 1.40 | 20.5±2.7 | 0.98 |
| 1.0 | 1832±0.4# | 1.24 | 37.8±2.2 | 1.00 | 1065±95 | 0.89 | 19.4±3.7 | 0.93 |
All cells were challenged with 15 ng/mL LPS.
2
OxC-beta concentration expressed using the molecular weight of ß-carotene.
3
Values determined by reference standards included in each assay.
4
Fold change relative to untreated cells (no OxC-beta).
# p<0.005, * p<0.05 (Student’s t-test versus untreated).