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. 2014 Oct 31;9(10):e111620. doi: 10.1371/journal.pone.0111620

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© 2014 Yan et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Original magnification, ×400. Few positive cells are observed in normal middle ear mucosa of the guinea pigs (A) and rats (D). Only some positive cells are seen in epithelial cells. In the TS group of the guinea pigs (B) and the rats (E), numerous positive cells are displayed in fibroblasts and inflammatory cells, and mainly locate in cytoplasm of fibroblasts and inflammatory cells. Only few positive cells could be seen in captopril and losartan treated group of guinea pigs (C) and rats (F). Arrow: positive cells.