Figure 6. MLA inhibition of Aβ-induced autophagy is mediated by mTOR signal pathway in SH-SY5Y cells.

(A) After exposure to different doses of Aβ_25–35, the level of phosphorylated p70S6K, a mTOR complex 1 substrate, was evaluated by western blot analysis. Signals were quantified by densitometry. (B) Western blot analysis of level of phosphorylated p70S6K after exposure to 10 µM Aβ_25–35 with or without MLA.