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. 2014 Oct 31;9(10):e111575. doi: 10.1371/journal.pone.0111575

Figure 7. Suppression of epithelial-mesenchymal transition (EMT) by the acetone extract of F. cucullata and usnic acid in sub-lethal concentrations.

Figure 7

(A) E-cadherin level in A549 cells treated with the F. cucullata extract, usnic acid, or lichesterinic acid for 48 hr, and quantificational analysis of E-cadherin band in each group. Values were obtained by measuring the intensity of E-cadherin band normalized to α-tubulin. (B) Quantitative analysis of the mRNA level of EMT markers in A549 cells treated with the F. cucullata extract, usnic acid, or lichesterinic acid for 48 hr. Data represent mean ± S.E.M. (standard error of the mean), n = 3. *p<0.05; **p<0.01; NS, no significant difference when compared to the dimethylsulfoxide-treated group; @p<0.05 when compared to the indicated group.