TABLE 3.
Comparison of enzyme activities of cellulosomes and noncellulosomal enzymes and their synergistic effects with different carbon sources
Carbon source and fractiona | Activity in each fractionb
|
|||||
---|---|---|---|---|---|---|
CMCase | Avicelase | Pectate lyase | Xylanase | CAXase | CFase | |
Cellulose | ||||||
Cellulosomes | 4.85 | 3.39 | 1.33 | 0.48 | 0.06 | 0.68 |
Noncellulosomal proteins | 1.29 | 4.22 | 1.60 | 0.62 | 0.15 | 0.84 |
C-NC mixture | 11.10 | 7.87 | 3.47 | 0.48 | 0.80 | 2.30 |
Synergy | 1.81 | 1.03 | 1.18 | 0.43 | 3.86 | 1.52 |
Cellulose-Pectin | ||||||
Cellulosomes | 3.04 | 1.64 | 0.40 | 0.55 | 0.14 | 0.15 |
Noncellulosomal proteins | 2.96 | 4.11 | 2.50 | 1.16 | 1.03 | 1.29 |
C-NC mixture | 14.38 | 8.80 | 3.37 | 3.37 | 1.21 | 1.26 |
Synergy | 2.40 | 1.53 | 1.16 | 1.96 | 1.04 | 0.87 |
Cellulose-xylan | ||||||
Cellulosomes | 4.49 | 2.15 | 0.40 | 1.64 | 0.27 | 0.51 |
Noncellulosomal proteins | 2.54 | 4.13 | 1.51 | 2.61 | 0.08 | 0.32 |
C-NC mixture | 17.04 | 9.29 | 3.32 | 4.28 | 0.64 | 1.40 |
Synergy | 2.42 | 1.48 | 1.73 | 1.01 | 1.83 | 1.68 |
Cellulose-pectin-xylan | ||||||
Cellulosomes | 2.44 | 1.14 | 0.45 | 0.49 | 0.05 | 0.19 |
Noncellulosomal proteins | 2.39 | 3.01 | 2.40 | 1.43 | 0.26 | 1.33 |
C-NC mixture | 11.19 | 6.94 | 1.49 | 0.60 | 0.76 | 2.59 |
Synergy | 2.32 | 1.67 | 0.52 | 0.31 | 2.42 | 1.71 |
Pectin | ||||||
Cellulosomes | 2.01 | 1.37 | 0.41 | 0.36 | 0.41 | 0.06 |
Noncellulosomal proteins | 3.83 | 5.69 | 3.67 | 0.52 | 1.26 | 0.40 |
C-NC mixture | 15.13 | 8.88 | 3.61 | 1.34 | 1.80 | 1.23 |
Synergy | 2.59 | 1.26 | 0.89 | 1.52 | 1.08 | 2.68 |
Xylan | ||||||
Cellulosomes | 2.06 | 0.81 | 0.04 | 0.54 | 0.56 | 0.03 |
Noncellulosomal proteins | 2.43 | 2.87 | 2.10 | 1.91 | 0.22 | 0.80 |
C-NC mixture | 10.18 | 5.61 | 1.95 | 3.11 | 2.10 | 0.94 |
Synergy | 2.26 | 1.53 | 0.91 | 1.27 | 2.67 | 1.13 |
CF | ||||||
Cellulosomes | 2.17 | 1.05 | 0.24 | 0.05 | 0.27 | 0.11 |
Noncellulosomal proteins | 4.87 | 2.20 | 2.04 | 0.93 | 1.73 | 0.47 |
C-NC mixture | 16.74 | 6.18 | 3.47 | 1.37 | 2.01 | 2.62 |
Synergy | 2.38 | 1.90 | 1.53 | 1.40 | 1.01 | 4.53 |
The fractions were purified from C. cellulovorans cultivated on medium containing 0.5% cellobiose, 1% cellulose (Avicel), 1% pectin, 1% xylan, 1% cellulose-pectin mixture (cellulose/pectin ratio of 3:2 [wt/wt]), 1% cellulose-xylan mixture (cellulose/xylan ratio of 3:2 [wt/wt]), 1% cellulose-pectin-xylan mixture (cellulose/pectin/xylan ratio of 3:1:1 [wt/wt]), or 1% CF as the sole carbon source. The fractions are cellulosomes, noncellulosomal proteins, and a mixture of cellulosomes and noncellulosomal proteins (C-NC mixture). The synergy in a mixture of cellulosomes and noncellulosomal proteins (cellulosome/noncellulosomal protein ratio of 1:1 [wt/wt]) was calculated by dividing the activity in the mixture by the activity in cellulosomes and noncellulosomal proteins.
The activities of CMCase, pectate lyase, xylanase, and CAXase are shown in milliunits per milliliter. The Avicelase activity and CFase activity are shown in milliunits per hour.