Table 3. Correlation of MyD88 and TLR4 with other clinical and pathological parameters.

Characteristic	MyD88 (low)	MyD88 (high)	?2	P	TLR4 (low)	TLR4 (high)	?2	P
Age, years			0.027	0.889			0.103	0.780
≤50	56	44			53	47
>50	60	45			58	47
Unknown	0	0			0	0
Menopausal status			0.113	0.778			0.762	0.402
Premenopausal	52	42			54	40
Postmenopausal	64	47			57	54
Unknown	0	0			0	0
Histological grade			2.053	0.195			1.034	0.337
G 1–2	91	62			86	67
G 3	25	27			25	27
Unknown	0	0			0	0
Tumor size			0.665	0.480			3.079	0.092
≤5	57	39			58	38
>5	58	50			52	56
Unknown	1	0			1	0
Lymph node			0.168	0.771
Negative	73	54			73	54	1.715	0.196
Positive	42	35			37	40
Unknown	1	0			1	0
ER			19.697	<0.001			4.092	0.058
Negative	59	72			64	67
Positive	57	17			47	27
Unknown	0	0			0	0
PR			24.027	<0.001			6.341	0.015
Negative	78	83			80	81
Positive	38	4			30	12
Unknown	0	2			1	1
HER-2			3.159	0.085			2.173	0.154
Negative	64	60			62	62
Positive	52	29			49	32
Recurrence or metastasis			14.892	<0.001			7.753	0.006
No	98	54			91	61
Yes	18	35			20	33
Unknown	0	0			0	0

Abbreviations: MyD88, myeloid differentiation primary response 88; TLR4, Toll-like receptor 4; G, Histological Grade; ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor receptor 2;

P-value was calculated with a two-sided χ2 test.

Bold values denote P≤0.05.