Table 4. Univariate analysis of potential factors predicting disease-free survival and overall survival in breast cancer patients.
Disease-free Survival | Overall Survival | |||
Variable | HR (95%CI) | P | HR (95%CI) | P |
Postmenopausal | 1.688 (0.953–2.989) | 0.073 | 3.778 (1.424–10.021) | 0.008 |
Histological grade ≥3 | 1.799 (1.023–3.164) | 0.042 | 2.209 (1.014–4.809) | 0.046 |
Tumor size >5 | 1.417 (0.817–2.457) | 0.215 | 1.907 (0.850–4.279) | 0.118 |
Lymph-node positive | 2.664 (1.529–4.641) | 0.001 | 5.357 (2.250–12.755) | <0.001 |
ER | 0.892 (0.507–1.569) | 0.692 | 0.731 (0.318–1.680) | 0.460 |
PR | 0.530 (0.239–1.175) | 0.118 | 0.472 (0.142–1.572) | 0.221 |
HER2 | 0.797 (0.453–1.430) | 0.432 | 0.512 (0.215–1.218) | 0.130 |
MyD88 | 3.416 (1.912–6.103) | <0.001 | 5.268 (2.114–13.128) | <0.001 |
TLR4 | 2.422 (1.384–4.238) | 0.002 | 3.916 (1.644–9.324) | 0.002 |
Abbreviations: MyD88, myeloid differentiation primary response 88; TLR4, Toll-like receptor 4; ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor receptor 2; HR, hazard ratio; CI, confidence interval.
P-value was calculated with a two-sided χ2 test.
Bold values denote P≤0.05.