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. 2014 Oct 31;9(10):e111639. doi: 10.1371/journal.pone.0111639

Table 4. Univariate analysis of potential factors predicting disease-free survival and overall survival in breast cancer patients.

Disease-free Survival Overall Survival
Variable HR (95%CI) P HR (95%CI) P
Postmenopausal 1.688 (0.953–2.989) 0.073 3.778 (1.424–10.021) 0.008
Histological grade ≥3 1.799 (1.023–3.164) 0.042 2.209 (1.014–4.809) 0.046
Tumor size >5 1.417 (0.817–2.457) 0.215 1.907 (0.850–4.279) 0.118
Lymph-node positive 2.664 (1.529–4.641) 0.001 5.357 (2.250–12.755) <0.001
ER 0.892 (0.507–1.569) 0.692 0.731 (0.318–1.680) 0.460
PR 0.530 (0.239–1.175) 0.118 0.472 (0.142–1.572) 0.221
HER2 0.797 (0.453–1.430) 0.432 0.512 (0.215–1.218) 0.130
MyD88 3.416 (1.912–6.103) <0.001 5.268 (2.114–13.128) <0.001
TLR4 2.422 (1.384–4.238) 0.002 3.916 (1.644–9.324) 0.002

Abbreviations: MyD88, myeloid differentiation primary response 88; TLR4, Toll-like receptor 4; ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor receptor 2; HR, hazard ratio; CI, confidence interval.

P-value was calculated with a two-sided χ2 test.

Bold values denote P≤0.05.