Skip to main content
. 2014 Oct 31;9(10):e111753. doi: 10.1371/journal.pone.0111753

Table 1. Parameters estimates and 95% confidence intervals of LKB and RS NTCP models for heart and lung dose volume histograms fitting.

D50 (Gy) m n rs AUC LLH
LKB heart 32.8 0.66 0.16 0.27 0.67 −51.6
(25.9, 44.7) (0.41, 1) (0.10, 0.89) (0.56, 0.78)
LKB lung 33.2 0.19 0.01 0.28 0.69 −49.7
(31.3–35.5) (0.13–0.32) (0.01–0.03) (0.58, 0.78)
D50 (Gy) γ s rs AUC LLH
RS heart 32.4 0.42 0.99 0.25 0.66 −52.3
(22.7, 48.5) (0.24, 0.62) (0.0–1.0) (0.55–0.76)
RS lung 24.4 2.12 0.99 0.26 0.66 −51.1
(22.3, 26.7) (0.3–3.8) (0.67–1.0) (0.55–0.76)

Abbreviation- LKB: Lyman-Kutcher-Burman, RS: Relative Seriality, NTCP: Normal Tissue Complication Probability, D50: uniform dose given to the entire organ volume that results in 50% complication probability, rs: Spearman’s correlation coefficient, AUC: the area under the receiver operator characteristic curve, LLH: log-likelihood (LLH).