Table 1. Parameters estimates and 95% confidence intervals of LKB and RS NTCP models for heart and lung dose volume histograms fitting.
D50 (Gy) | m | n | rs | AUC | LLH | |
LKB heart | 32.8 | 0.66 | 0.16 | 0.27 | 0.67 | −51.6 |
(25.9, 44.7) | (0.41, 1) | (0.10, 0.89) | (0.56, 0.78) | |||
LKB lung | 33.2 | 0.19 | 0.01 | 0.28 | 0.69 | −49.7 |
(31.3–35.5) | (0.13–0.32) | (0.01–0.03) | (0.58, 0.78) | |||
D50 (Gy) | γ | s | rs | AUC | LLH | |
RS heart | 32.4 | 0.42 | 0.99 | 0.25 | 0.66 | −52.3 |
(22.7, 48.5) | (0.24, 0.62) | (0.0–1.0) | (0.55–0.76) | |||
RS lung | 24.4 | 2.12 | 0.99 | 0.26 | 0.66 | −51.1 |
(22.3, 26.7) | (0.3–3.8) | (0.67–1.0) | (0.55–0.76) |
Abbreviation- LKB: Lyman-Kutcher-Burman, RS: Relative Seriality, NTCP: Normal Tissue Complication Probability, D50: uniform dose given to the entire organ volume that results in 50% complication probability, rs: Spearman’s correlation coefficient, AUC: the area under the receiver operator characteristic curve, LLH: log-likelihood (LLH).