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. 2014 Oct 31;9(10):e111816. doi: 10.1371/journal.pone.0111816

Table 2. Genotype distributions in 985 aspirin-treated patients with stable coronary artery disease.

Gene Gene product Nucleotide change1 Ref SNP ID2 Minor allele MAF Call rate, % Hardy-Weinberg equilibrium3
ITGB3 GP IIIa PlA1/A2 (T1565→C) rs5918 C 0.17 98.8 0.98
PTGS1 COX-1 A-842→G/C50→T rs10306114 G 0.07 98.8 0.72
PTGS1 COX-1 C22→T rs1236913 T 0.08 98.8 0.34
TBXA2R TXA2 receptor C924→T rs4523 A 0.33 98.6 1.0
TBXA2R TXA2 receptor C795→T rs1131882 A 0.14 98.6 0.96
P2RY1 P2Y1 C893→T rs1065776 T 0.04 98.6 0.98
P2RY1 P2Y1 A1622→G rs701265 G 0.14 98.8 1.0
P2RY12 P2Y12 H2 haplotype rs68096994 A 0.15 98.5 0.35
P2RY12 P2Y12 H2 haplotype rs10935838d4 A 0.15 96.3 0.35
P2RY12 P2Y12 H2 haplotype rs20469344 G 0.18 98.5 0.008
GP1BA GP Iba C145→T (HPA-2) rs6065 T 0.07 98.6 0.90
GP6 GP VI T13254→C rs1613662 G 0.17 98.6 0.94
PLA2G7 Platelet-activating factor acetylhydrolase G994→T rs1051931 A 0.21 96.8 0.84
F13A1 Coagulation factor XIII G34→T rs5985 A 0.26 98.6 0.78
PEAR1 Platelet endothelial aggregation receptor-1 A→G rs12041331 A 0.08 97.1 0.98
PEAR1 Platelet endothelial aggregation receptor-1 A→C rs2768759 A 0.26 98.6 0.38
1

Nucleotide change or alternative name as most often termed in the existing literature. 2According to the NCBI SNP database, dbSNP: http://www.ncbi.nlm.nih.gov/projects/SNP/ (accessed on August 15, 2014). 3P-values refer to the goodness-of-fit χ2 test for deviation from the Hardy-Weinberg equilibrium. 4Included in the H1/H2 haplotype constituted by rs10935838, rs2046934, rs5853517, and rs6809699 [35]. COX: cyclooxygenase, GP: glycoprotein, MAF: minor allele frequency, SNP: single nucleotide polymorphism, TXA2: thromboxane A2.