Table 4. Cyclooxygenase-1 activity and platelet activation according to PEAR1 rs12041331 genotype.
| rs12041331 genotype | Thromboxane B2 (ng/mL)1 | P-value | P-selectin (ng/mL) | P-value |
| GG | 0.97 (0.91–1.03) | 74.3±24.9 | ||
| GA | 1.06 (0.90–1.24) | 0.28 | 78.6±28.4 | 0.05 |
| AA | 1.15 (0.15–8.81) | 78.3±18.7 |
Values are mean ± standard deviation unless otherwise stated. Patients homozygous for the variant allele were pooled with heterozygotes and analyses are made according to the unpaired t-test. 1Logarithm transformed for analysis and back-transformed for presentation as geometric mean (95% confidence interval).