Table 2.
Adjusted change in child BMI z-score between 2–5 years of age (β) by tercile of or with a 10-fold increase in maternal or early childhood urinary BPA concentrations among Cincinnati, Ohio, women and their children.a
BPA exposure measure | n | Mean BMI z-score | β (95% CI) | p-Value |
---|---|---|---|---|
Prenatal | ||||
1st tercile (0.4–1.6 μg/g creatinine) | 99 | 0.00 | Referent | Referent |
2nd tercile (1.6–2.6 μg/g creatinine) | 99 | –0.01 | 0.0 (–0.3, 0.3) | 0.98 |
3rd tercile (2.6–49 μg/g creatinine) | 99 | 0.05 | 0.1 (–0.2, 0.3) | 0.66 |
Continuous, log10-transformed | 297 | –0.1 (–0.5, 0.3) | 0.51 | |
Early childhood | ||||
1st tercile (2.1–11 μg/g creatinine) | 95 | 0.13 | Referent | Referent |
2nd tercile (11–20 μg/g creatinine) | 95 | 0.12 | 0.0 (–0.3, 0.3) | 0.96 |
3rd tercile (20–314 μg/g creatinine) | 95 | –0.10 | –0.2 (–0.5, 0.1) | 0.12 |
Continuous, log10-transformed | 285 | –0.2 (–0.6, 0.1) | 0.19 | |
aAdjusted for maternal race (white, black, and other), marital status (married living together, unmarried living together, and unmarried living alone), parity (0, 1, and ≥ 2), age at delivery (continuous, years), household income (continuous, $10,000 increments), education (< high school, high school, some college, and ≥ bachelor’s degree), employment (any and none), insurance (private and public/none), BMI at 16 weeks of pregnancy (continuous, kg/m2), depressive symptoms at baseline (continuous), and prenatal serum cotinine (continuous, log1-transformed). |