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. 2014 May 20;57(11):4805–4818. doi: 10.1021/jm500311e

Figure 8.

Figure 8

Dependence of the equilibrium dissociation constant of β-SPGG-2–DEGR-factor XIa complex on the concentration of sodium ion in the medium at pH 7.4 and 37 °C. The KD,obs of β-SPGG-2 (◇), UFH (○), and H8 (□) binding to DEGR-factor XIa was measured through spectrophotometric titrations. Solid lines represent linear regression fits using eq 5. Error bars in symbols represent standard deviation of the mean from at least two experiments. Symbols without apparent error bars indicate that the standard error was smaller than the size of the symbol.