Table 3. Activities of Compounds against L. donovani Clinical Isolatesa.
| EC50, μM |
||
|---|---|---|
| compd | BPK206/0 | BPK164/1 |
| sodium stibogluconateb | 24 ± 6 | >60 |
| 15 | 2.8 ± 0.4 | 2.0 ± 0.4 |
| 16 | 2.0 ± 0.7 | 1.4 ± 0.3 |
| 23 | 4.2 ± 0.0 | 3.8 ± 0.6 |
Mean ± range of two independent measurements.
Values for sodium stibogluconate are given in micrograms of pentavalent antimony per milliliter.