Table 2. Association between cognitive function and resting blood flow velocity, conventional CO2 vasoreactivity and autoregulation indices.
| Resting BFV | CO2 vasoreactivity | CVR change (sit-to-stand) | |
|---|---|---|---|
| β (SE), p-value | β (SE), p-value | β (SE), p-value | |
| TMT, Part A | 0.001(0.01), p=0.69 | -0.4(0.2), p=0.03 | 0.2(0.1), p=0.05 |
| TMT, Part B | -0.01(0.01), p=0.31 | -0.7(0.3), p=0.009 | -0.02(0.14), p=0.91 |
| TMT, Part B-A | -0.02(0.02), p=0.34 | -0.9(0.4), p=0.02 | -0.13(0.21), p=0.53 |
| HVLT, Recall | 0.11(0.07), p=0.13 | 0.4(1.8), p=0.83 | 0.95(0.9), p=0.3 |
| HVLT, recognition | 0.003(0.05), p=0.95 | 0.07(1.1), p=0.95 | 0.21(0.59), p=0.73 |
| Digit Span, Forward | -0.05(0.04), p=0.19 | -0.5(0.9), p=0.56 | -0.19(0.47), p=0.69 |
| Digit Span, Backwards | 0.2(0.22), p=0.38 | 0.5(1), p=0.61 | 0.3(0.54), p=0.59 |
BFV: Blood flow velocity; CVR : Cerebrovascular resistance; SE= standard error; TMT=Trail Making Test; B-A: Part B minus Part A; HVLT: Hopkins Verbal Learning Test. Slope (β), standard errors and p-values were obtained from the regression models adjusted for age and systolic blood pressure. TMT (A, B, and B-A) were transformed using a logarithmic transformation due to their skewed distribution.