Table 3. Association between cognitive function and PDM derived indices of cerebrovascular reactivity and pressure autoregulation.
CO2 Vasoreactivity | Pressure Autoregulation | |
---|---|---|
β (SE), p-value | β (SE), p-value | |
TMT, Part A | 0.02(0.04), p=0.63 | 0.09(0.06), p=0.15 |
TMT, Part B | -0.11(0.06), p=0.05 | 0.04(0.08), p=0.68 |
TMT, Part B-A | -0.22(0.08), p=0.01 | 0.01(0.13), p=0.95 |
HVLT, Recall | 0.4(0.38), p=0.3 | 0.04(0.54), p=0.94 |
HVLT, recognition | 0.35(0.24), p=0.16 | -0.22(0.35), p=0.53 |
Digit Span, Forward | -0.16(0.2), p=0.42 | -0.42(0.27), p=0.13 |
Digit Span, Backwards | 0.2(0.22), p=0.38 | -0.16(0.32), p=0.63 |
SE= standard error; TMT=Trail Making Test; B-A: Part B minus Part A; HVLT: Hopkins Verbal Learning Test; Slope (β), standard errors and p-values were obtained from the regression models adjusted for age and systolic blood pressure. TMT (A, B, and B-A) were transformed using a logarithmic transformation due to their skewed distribution.