Skip to main content
. 2014 Jun 24;11(8):2703–2712. doi: 10.1021/mp5002312

Table 2. PK Parameters of Sali after It Was Delivered As a Free Form or an Encapsulated Form in the NP3.

  Sali iTEP–Sali NP3
  mean 95% CI mean 95% CI
initial vol of distribn (V0, μL/g) 197.44 166.82–241.84 118.78 107.57–132.63
AUC (μM h) 30.70 14.15–53.28 192.10 98.34–315.27
clearance (CL, μL/(h g)) 216.87 124.96–470.52 34.66 21.12–67.70
elimination half-life (telimi, h) 0.86 0.26–2.57 4.45 2.77–7.70
distribn half-life (tdistribn, h) 0.43 0.29–1.19 0.63 0.40–1.08
R2 0.93   0.95