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. 2014 Oct 20;14:267. doi: 10.1186/s12866-014-0267-6

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© Lima et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creationcommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Protein interaction network of the iron-responsive proteome. The protein input was the data obtained from the proteomics analysis. Only the proteins that were up-regulated or exclusively identified in the iron responsive proteome were used in the construction of the protein-protein interaction network. The red and blue nodes represents the two clusters obtained with the MCODE plug-in, in which the red ones are the proteins related to energetic metabolism and the blue dots are ribosomal proteins.