Table 2.
Laboratory parameters
| Parameter | Group | Baseline | 60 min | 120 min | 180 min | 240 min |
|---|---|---|---|---|---|---|
| Natrium | C-group | 139.4 (1.4) | 139.1 (1.5) | 139.1 (2.4) | 139.1 (2.4) | 138.2 (1.4)** |
| (mmol/l) | P-group | 139.0 (1.5) | 138.9 (1.8) | 138.4 (2.3) | 138.0 (3.2) | 138.0 (2.1) |
| Kalium | C-group | 4.2 (0.2) | 4.4 (0.3)* | 4.6 (0.3)** | 4.9 (0.3)*** | 5.3 (0.5)*** |
| (mmol/l) | P-group | 4.3 (0.5) | 4.5 (0.5)* | 5.0 (0.7)** | 5.9 (1.2)* | 6.1 (0.9)*** |
| Chloride | C-group | 99.1 (1.4) | 98.6 (0.9) | 98.6 (0.9) | 99.4 (1.1) | 98.6 (1.1) |
| (mmol/l) | P-group | 99.2 (1.3) | 98.5 (1.2) | 98.6 (2.3) | 98.1 (2.0) | 98.9 (1.7) |
| Osmolalitet | C-group | 285.8 (2.4) | 288.4 (6,6) | 283.8 (1.8) | 282.8 (3.6) | 284.5 (4.9) |
| (mosm/l) | P-group | 282.4 (4.6) | 281.9 (2.7) | 283.1 (3.6) | 284.3 (3.2) | 285.9 (4.7) |
| s-Protein | C-group | 47.0 (2.1) | 46.4 (2.1) | 44.5 (2.1)** | 43.4 (1.8)*** | 43.3 (1.2)** |
| (g/l) | P-group | 46.9 (3.1) | 49.3 (3.4)* | 47.9 (3.2) | 47.9 (4.4) | 47.8 (3.6)# |
| s-Albumin | C-group | 31.1 (4.3) | 30.9 (4.0) | 29.5 (4.3)** | 29.8 (3.7) | 28.9 (3.4)* |
| (g/l) | P-group | 31.4 (2.9) | 32.6 (3.0) | 31.9 (2.4) | 32.3 (2.4) | 32.3 (2.7) |
| Albuminmass | C-group | 2,02 (0.42) | 1.98 (0.39) | 1.89 (0.37)* | 1.93 (0.37) | 1.87 (0.41)** |
| (g/kg) | P-group | 1.86 (0.21) | 1.76 (0.22)** | 1,71 (0.21)*** | 1.52 (0.21)*** | 1.45 (0.19)*** |
| Proteinmass | C-group | 3.03 (0.3) | 2.97 (0.31) | 2.84 (0.28)* | 2.8 (0.25)* | 2.78 (0.32)* |
| (g/kg) | P-group | 2.79 (0.41) | 2.67 (0.43)** | 2.59 (0.41)*** | 2.28 (0.43)*** | 2.16 (0.33)#*** |
| Hemoglobin | C-group | 8.0 (0.6) | 7.8 (0.6)## | 7.9 (0.8)# | 7.9 (0.9)### | 7.7 (0.8) ### |
| (g/100 ml) | P-group | 8.6 (0.6) | 9.1 (0.6)** | 9.2 (0.8)** | 9.9 (0.6)*** | 10.1 (0.7)*** |
| pH | C-group | 7.50 (0.04) | 7.50 (0.03) | 7.51 (0.04) | 7.50 (0.03) | 7.51 (0.02)## |
| P-group | 7.52 (0.05) | 7.50 (0.04) | 7.49 (0.04) | 7.45 (0.06) | 7.43 (0.05)* | |
| BE | C-group | 7.74 (1.5) | 8.08 (1.5) | 8.31 (1.2) | 8.49 (1.1)## | 7.81 (1.1)## |
| (mmol/l) | P-group | 7.65 (1.1) | 7.36 (1.1) | 6.85 (1.0) | 5.68 (1.5) | 5.29 (1.2)* |
| P a CO 2 | C-group | 5.3 (0.5) | 5.5 (0.4) | 5.3 (0.5) | 5.5 (0.5) | 5.2 (0.5)# |
| (kPa) | P-group | 5.1 (0.7) | 5.3 (0.6) | 5.4 (0.4) | 5.8 (0.9) | 6.2 (0.7) |
| HCO 3 - | C-group | 31.5 (1.4) | 31.8 (1.4) | 32.1 (1.1) | 32.2 (1.0)# | 31.6 (0.9)## |
| (mmol/l) | P-group | 31.4 (0.9) | 31.2 (1.1) | 30.7 (1.0) | 29.7 (1.7) | 29.1 1.3)* |
| P a O 2 | C-group | 34.4 (11.9) | 28.1 (5.4) | 26.9 (4.0) | 26.0 (4.8) | 26.2 (5.6) |
| (kPa) | P-group | 25.8 (4.9) | 24.7 (4.0) | 24.1 (5.5) | 24.8 (4.5) | 22.7 (5.3) |
| TNF-α | C-group | 72.0 (28.9) | 79.5 (27.3) | 83.0 (27.0) | 77.1 (24.1) | 80.7 (29.0) |
| (pg/ml) | P-group | 56.8 (21.1) | 63.2(19.4) | 64.7 (22.1) | 87.8 (29.6)** | 91.4 (38.4)* |
| Interleukin-6 | C-group | 3.6 (4.7) | 9.0 (3.4)** | 17.6 (3.4)*** | 23.9 (8.0)*** | 30.2 (14.5)** |
| (pg/ml) | P-group | 10.5 (7.8) | 16.5 (11.8)** | 30.9 (13.1)*** | 52.8 (26.2)*** | 83.0 (64.4) |
Results as means with SD in parentheses; Control group: C-group; Intervention group: P-group; *:P<0.05 **:P<0.01 ***:P<0.001; within group differences compared with baseline values; #:P<0.05 ##:P<0.01 ###:P<0.001; between group differences, same time.