Table I.
Indicates effect of administration of oral morphine on placenta and plasma corticosterone concentration in rats
| Placenta/Day |
Maternal
thickness ( µm) |
Fetal thickness
( µm) |
Maternal cell
number (count/ unit) |
Fetal cell
number (count/ unit) |
Maternal
lacuna area ( µ ²) |
Fetal
Lacuna area (µ ²) |
Plasma concentration
(ml ) |
|---|---|---|---|---|---|---|---|
| Control 10th | 873.85 ±114 | 677.6 ±36 | 13 ±0.1 | 5±0.1 | 45307 ± 0.1 | 27046 ±0.1 | - |
| Experiment 10th | 1064.55 ±197* | 205.2 ±33* | 13 ±0.1** | 7 ± 0.1* | 20300 ± 1210** | 19525±491** | - |
| Control 14th | 574.92 ±26 | 1394.67±0 | 17±1 | 17 ± 0.5 | 21979.3 ±317 | 7970.54 ±164 | - |
| Experiment 14th | 2351 ±173*** | 533. ±0*** | 24±5** | 24±2* | 21935.5 ±242 | 8383.1 ±118 | - |
| Plasma Control 13th | - | - | - | - | - | - | 650 ± 45 |
| Plasma Experiment 13th | - | - | - | - | - | - | 1230 ±52** |
Result were considered statistically significant when p< 0.05. (Mean ± SEM).
Effect of administration of oral morphine on the10, 14th days of placenta portions thickness and cell number and lacuna area development furthermore, Plasma corticosterone concentration in rats which received oral morphine on the 13th day of pregnancy and comparison of control and experimental groups.