FIG. 4.
Sequence of the antisense target region of three clones with a high mutation rate. Three clones, BT-P1, BT-P2, and BT-P3 (Table 2) that had significantly higher mutation rates than wt HIV were sequenced. The nucleotide changes are shown and are predominantly A-G transitions. The antisense target region is shown in bold black, and the underlined region represents the V3 loop. Mutations were concentrated within the antisense target region.