TABLE 3.
Conserved genes in baculovirus genomesd
| Gene function | Genes present in all baculovirusesa | Genes present in all lepidopteran baculoviruses and NeleNPV | Genes present in all lepidopteran baculoviruses but not in NeleNPV |
|---|---|---|---|
| Replication | lef-2 (ac6), lef-1 (ac14), dnapol (ac65), helicase (ac95) | dbp1 (ac25) | lef-3 (ac67), me53 (ac139), ie-1 (ac147) |
| Transcription | p47 (ac40), lef-8 (ac50), lef-9 (ac62), vlf-1 (ac77), lef-4 (ac90), lef-5 (ac99) | lef-11 (ac37) | lef-6 (ac28), pp31/39K (ac36) |
| Structural proteins | vp1054 (ac54), gp41 (ac80), vp91/p95 (ac83), vp39 (ac89), p6.9 (ac100), p74 (ac138), odv-e27 (ac144), odv-e56 (ac148), | polh (ac8), odv-e18 (ac143) | ac23/ld130b, odv-e66 (ac46), fp25K (ac61), odv-e25 (ac94), pk1 (ac10) |
| Per os infectivity factorsc | pif (ac119) | ||
| pif-2(ac22) | |||
| Auxiliary | alk-exo (ac133) | fgf (ac32), ubiquitin (ac35) | |
| Unknown | ac68, ac81, ac92, ac96, 38K (ac98), ac109, ac115, ac142 | ac53, ac76, ac78, ac93, p40 (ac101), ac106, p45 (ac103), ac145 | 38.7K (ac13), ac29, ac38, ac66, ac75, ac82, p12 (ac102), ac110, ac146, |
a
Based on the genomes of 22 completely sequenced baculoviruses as listed in the text.
b
CuniNPV, a dipteran baculovirus, also has a potential ld130 homologue.
c
P74 is listed as a structural protein but is also necessary for per os infectivity.