FIG. 2.

Inhibition of CAV9 binding to purified integrins α_vβ₃ and α_vβ₆ by RGD peptides. (A) CAV9 binding to integrin α_vβ₃. (B) CAV9 binding to integrin α_vβ₆. The peptides used were GRGDSP, GRGESP*, QSRRRGDMST (based on the CAV9 VP1 C terminus), and NGKKKNWKKIM (a control peptide based on part of the HPeV1 VP3 protein). The y axis represents binding in the presence of the appropriate peptide as a percentage of binding without added peptide. The GRGESP peptide was used only at a concentration of 100 μM in the α_vβ₃ experiment.