. Author manuscript; available in PMC: 2014 Nov 1.

Published in final edited form as: Int Forum Allergy Rhinol. 2012 Dec 19;3(6):474–481. doi: 10.1002/alr.21125

Table 3.

Characteristics of Included Studies

Study	n	Inclusion	Exclusion	Indication	Age (Mean in years)	Anesthetic and narcotic combination used
Eberhart 2003 ¹⁸	88	ASA grade 1 or 2, undergoing ESS	n/a	Diffuse polypoid pansinusitis, Chronic sinusitis	33	Propofol/remifentanil vs. isoflurane/alfentanil
Tirelli 2004 ²¹	64	ASA grade 1 or 2 undergoing ESS	n/a	Simple chronic sinusitis, chronic sinusitis with polyposis	TIVA- 48 INA- 45	Propofol/remifentanil vs. Isoflurane/fentanyl
Wormald 2005 ²³	56	ASA grade 1 or 2, undergoing ESS	Receiving cardiovascular active medications and anticoagulation medications	Allergic fungal sinusitis, nasal polyposis, chronic rhinosinusitis	n/a	Propofol/remifentanil vs sevoflurane/fentanyl
Beule 2007 ²⁰	46	ASA grade 1 or 2, 18–75 yo, Polypoid chronic pansinusitis without allergic mucin (LM ≥ 12), refractory to medical management	Noninflammatory disease of paranasal sinus, allergy to anesthetic, medication or condition associated with impaired hemostasis, altered coagulation factors, pre or intraoperative use of NSAIDs, sympathomimetics, colloids	Chronic rhinosinusitis with nasal polyposis	TIVA- 43 INA- 46	Propofol/fentanyl vs. sevoflurane/fentanyl
Ahn 2008 ²²	40	ASA grade 1 or 2, undergoing ESS	Disease or medication related to coagulation or cardiovascular system	Chronic sinusitis with ≥ 2 sinuses involved	TIVA- 49 INA- 41	Propofol/remifentanil vs. sevoflurane/remifentanil
Yoo 2010 ¹⁹	60	ASA grade 1 or 2, undergoing ESS	BMI ≥30, alcohol/drug abuse, pregnancy, meds that impact MAC, communication problems, allergic fungal sinusitis, nasal polyposis	n/a	TIVA- 37 INA (sevo)- 43 INA (des)- 43	Propofol/remifentanil vs. sevoflurane/remifentanil vs. desflurane/remifentanil
Ankichetty 2011 ¹⁷	40	ASA grade 1 or 2, aged 16–60 years old, undergoing ESS	Bleeding disorder, receiving anticoagulation therapy, prior ESS, major hepatic, renal or CV disease	n/a	TIVA- 32 INA- 34	Propofol/fentanyl vs. isoflurane/fentanyl

Abbreviations: ASA - American Society of Anesthesiologists, ESS - Endoscopic sinus surgery, n/a - not available, TIVA - total intravenous anesthesia, INA - inhaled anesthesia, CV -Cardiovascular, LM - Lund-Mackay score, BMI - body mass index, sevo- sevoflurane, des - desflurane.