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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Genes Chromosomes Cancer. 2013 Nov 25;53(2):129–143. doi: 10.1002/gcc.22125

Table 1.

Summary of the interphase FISH results in the selected OSCC cell lines. Interphase FISH was used to assess copy number of ATM, MRE11A, H2AFX and CHEK1 genes relative to the chromosome 11 centromere.

Percentage of Cells with Copy Number Loss of *
Cell Line MRE11A
11q21
(94150466 -
94227040)		 ATM
11q22-q23
(108093559 -
108239826)		 H2AFX
11q23.3
(118964584 -
118966177)		 CHEK1
11q24.2
(125495031-
125546150)
UPCI:SCC029B+ 90 92 97 99
UPCI:SCC040+ 100 99 99 99
UPCI:SCC084+ 95 93 98 97
UPCI:SCC131+ 98 92 96 98
UPCI:SCC136+ 99 92 91 96
UPCI:SCC104 1 98 96 1
UPCI:SCC081+ 8 22 97 4
UPCI:SCC066 20 3 13 15
UPCI:SCC116 14 15 16 10
*

Lower ratio of test gene relative to the copy number of the chromosome 11 centromere.

+

These cell lines express CCND1 amplification.