Table 1.
Treatment Overview
| Surgery | Chemoradiotherapy | Maintenance | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ~30 Days | Radiation Therapy | ~30 Days | |||||||||||||||||
| Week | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 11 | 17 | 23 | 27 | 33 | 39 | 43 | 49 | 55 | |||
| Chemotherapy | V | V | V | V | V | V | A | A | B | A | A | B | A | A | B | ||||
V= Vincristine 1.5mg/m2 (1 dose)
A= Cisplatin 75mg/m2(1 dose), Lomustine 75mg/m2(1 dose), and Vincristine 1.5mg/m2(3doses)
B = Cyclophosphamide 1000mg/m2(2 doses) and Vincristine 1.5m/m2(2doses)
Adapted from COG protocol ACNS0331.