Table 2.
Changes in rheumatoid arthritis activity measures during the study.*
| Measure (possible range) |
Baseline | Follow-up | Mean change |
SRM (95% CI) | Mean change by Improvement category |
P (ANOVA) |
||
|---|---|---|---|---|---|---|---|---|
| Improved | Stayed the same |
Worsened | ||||||
| Patient global assessment (0 – 100) |
55.6 ± 25.2 | 37.6 ± 24.0 | −18.0 ± 26.4 | −0.68 (−0.60, −0.77) | −24.7 | −7.2 | 3.1 | <.0001 |
| Pain (0 – 100) | 60.5 ± 25.3 | 39.7 ± 27.0 | −21.0 ± 30.3 | −0.69 (−0.61, −0.78) | −29.7 | −8.2 | 2.2 | <.0001 |
| HAQ (0 – 3) | 1.4 ± 0.7 | 1.0 ± 0.7 | −0.4 ± 0.6 | −0.65 (−0.58, −0.72) | −0.63 | −0.08 | 0.06 | <.0001 |
| DAS28-ESR (0 – 9.4) | 6.16 ± 1.2 | 4.84 ± 1.38 | −1.31 ± 1.34 | −0.98 (−0.90, −1.07) | −1.67 | −0.62 | −0.2 | <.0001 |
| DAS28-CRP (1 – 9.4) | 5.55 ± 1.09 | 4.34 ± 1.26 | −1.23 ± 1.30 | −0.95 (−0.87, −1.04) | −1.60 | −0.59 | −0.06 | <.0001 |
| SDAI (0 – 86) | 38.6 ± 14.8 | 24.0 ± 13.9 | −14.9 ± 15.3 | −0.97 (−0.90, −1.07) | −19.3 | −7.4 | −1.28 | <.0001 |
| CDAI ( 0 – 76) | 36.8 ± 13.5 | 23.0 ± 13.6 | −13.7 ± 14.1 | −0.98 (−0.90, −1.08) | −18.0 | −6.7 | −1.2 | <.0001 |
*
SRM = standardized response mean; CI = confidence interval; ANOVA = analysis of variance; HAQ = Health Assessment Questionnaire Disability Index; DAS28-ESR = Disease Activity Score 28 Erythrocyte Sedimentation Rate; DAS28-CRP = Disease Activity Score 28 C-reactive Protein; SDAI = Simplified Disease Activity Index; CDAI = Clinical Disease Activity Index.
Plus-minus values are mean ± standard deviation.