Table 5.
Variables | Af (+)/IgE(+) (24 cases) | Af (−)/IgE(+) (51 cases) | Af (−)/IgE(−) (67 cases) |
---|---|---|---|
Age (yr) | 76(11,54 ~ 90) | 74(10,55 ~ 88) | 77(7,58 ~ 89) |
Smoking index (pack-yr) | 47(20,10 ~ 90) | 48(23,10 ~ 100) | 48(25,10 ~ 120) |
Chronic cough/sputum history (yr) | 19(13,2 ~ 40) | 17(13,2 ~ 45) | 19(12,2 ~ 40) |
Dyspnea history (yr)♦ | 8.8(5.6,1 ~ 20)* | 7.1(5.2,1 ~ 20)* | 3.7(3.7,0 ~ 20) |
Ratio of dyspnea history to chronic cough/sputum history♦ | 0.52(0.22,0.2 ~ 1)* | 0.47(0.19,0.07 ~ 1)* | 0.19(0.14,0 ~ 0.5) |
Occurrence of wheezing, n(%) | 21(88) | 44(86) | 45(67) |
FEV1/FVC% | 44(13,23 ~ 67) | 43(10,28 ~ 64) | 48(11,22 ~ 69) |
FEV1%predicted♦ | 37(14,14 ~ 68)# | 37(11,19 ~ 64)* | 44(14,20 ~ 79) |
GOLD stage♣ | |||
Stage II, n(%) | 3(12.5) | 9(17.6) | 22(32.8) |
Stage III, n(%) | 12(50.0) | 25(49.0) | 35(52.2) |
Stage IV, n(%) | 9(37.5) | 17(33.3) | 10(14.9) |
*Compared with Af(−)/IgE(−), P < 0.01.
#Compared with Af(−)/IgE(−),P <0.05.
♦Overall comparison among three groups, P <0.01.
♣Overall comparison among three groups, P <0.05.
Definition of abbreviations:
Af(+)/IgE(+): Aspergillus fumigatus hypersensitivity with elevated serum total IgE.
Af(−)/IgE(+): no Aspergillus fumigatus hypersensitivity but with elevated serum total IgE.
Af(−)/IgE(−): no Aspergillus fumigatus hypersensitivity with normal serum total IgE.
FEV1: Forced expiratory volume in 1 second, FVC: Forced vital capacity.