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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Clin Cancer Res. 2014 May 6;20(21):5537–5546. doi: 10.1158/1078-0432.CCR-13-3003

Table 1.

Mutations in 16 pairs of matched metastases

Patient Brain metastases Extracranial metastases
02 BRAF V600E BRAF V600E
03 None None
04 BRAF V600E BRAF V600E
05 BRAF V600K BRAF V600K
06 NRAS Q61K NRAS Q61K
07 BRAF V600E BRAF V600E
08 NRAS Q61K,
CTNNB1 S45F
NRAS Q61K
CTNNB1 S45F
09 None None
10 CTNNB1 S45P CTNNB1 S45P
11 BRAF V600E BRAF V600E
12 BRAF V600E BRAF V600E
13 None None
14 None None
15 BRAF V600E BRAF V600E
16 None None
17 NRAS Q61H NRAS Q61H*
*

One of the two replicate assays called NRAS Q61H.