FIG. 4.

Merged images of HSV-1-infected cells stained with antibodies detecting Hsc70 (red) and the viral ICP0 protein (green). Times (in hours) postadsorption are indicated above each panel. (A to C) Infected cells cultured at 37°C; (D to F) infected cells cultured at 39.5°C. In panels C and F, the white arrows indicate ICP0-stained foci that did not costain with Hsc70 and likely represent ND10. The red arrows indicate foci that costained with antibodies recognizing either Hsc70 or ICP0. In panel D, note the colocalization (yellow) between ICP0 and Hsc70 within the nucleolus.