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HIV-1 LTR promoter and CATA boxes of different subtypes. (A) Proviral genome of HIV-1 (not to scale). (B) Part of the LTR promoter and the consensus sequence of the TATA box with flanking nucleotides. The only variation within the TATA box is the T/A polymorphism at position 5 in subtype E versus all other subtypes. The HIV-1 TATA box is known as the TATAAGC motif (positions 3 to 9), but we demonstrate in this study that the motif is in fact CATATAA (positions 1 to 7).
